Table 2. Neoplasia characteristics of the lesions detected in the study.
| Number of colonoscopies performed | 69 |
| Procedures with neoplasia (%) | 13/69 (19) |
| Number of biopsies containing neoplasia | 19 |
| Targeted biopsies | |
| Total number of targeted biopsies (HDE only1, pCLE only2, both HDE/pCLE3) | 37 (13/7/17) |
| Containing neoplasia (%) | 17/37 (46) |
| All lesions identified by HDE | 30 |
| Containing neoplasia (%) | 13/30 (43) |
| All lesions identified by pCLE | 24 |
| Containing neoplasia (%) | 17/24 (71) |
| Lesions identified by both HDE and pCLEc | 17 |
| Containing neoplasia (%) | 13/17 (76) |
| Random biopsies | |
| Number of analyzed random biopsy locations | 607 |
| Total number of analyzed random biopsies | 2428 |
| Containing neoplasia (%) | 2 (0.08) |
| Number of random biopsies classified as dysplasia suspicion by pCLE off-line | 17 |
| Containing neoplasia (%) | 0 |
| Lesions containing neoplasia | |
| Endoscopically visible lesions with LGD (%) | 13/19 (68) |
| Endoscopically non-visible lesions with LGD (%) | 6/19 (32) |
| HGD | 0 |
| CRC | 0 |
CRC, colorectal cancer; HDE, high definition endoscopy; HGD, high-grade dysplasia, LGD, low-grade dysplasia; pCLE, probe-based laser endomicroscopy.
1
Dysplasia suspicion only in HDE, in pCLE- no dysplasia suspicion.
2
Dysplasia suspicion only in pCLE, in HDE- no dysplasia suspicion.
3
Dysplasia suspicion in both: HDE and pCLE.