Table 1.
Protein-coding genes with the highest G scores
| Gene
|
Length
|
Observed
|
Expected
|
G
|
Annotation
|
|---|---|---|---|---|---|
| pykF | 1413 | 19 | 0.16 | 180 | pyruvate kinase |
| iclR | 825 | 13 | 0.10 | 128 | transcriptional repressor, glyoxylate bypass |
| spoT | 2109 | 14 | 0.25 | 113 | stringent response |
| nadR | 1233 | 12 | 0.14 | 106 | bifunctional transcriptional repressor and NMN adenylyltransferase |
| hslU | 1332 | 11 | 0.16 | 94 | molecular chaperone and ATPase component of protease |
| yijC (fabR) | 705 | 7 | 0.08 | 62 | transcriptional repressor, fatty acid and phosphatidic acid pathway |
| topA | 2598 | 8 | 0.30 | 52 | DNA topoisomerase I subunit |
| malT | 2706 | 8 | 0.32 | 52 | transcriptional activator, maltotriose-ATP-binding |
| mrdA | 1902 | 7 | 0.22 | 48 | transpeptidase in peptidoglycan synthesis |
| mreB | 1044 | 6 | 0.12 | 47 | longitudinal peptidoglycan synthesis |
| infB | 2673 | 7 | 0.31 | 44 | translation initiation factor IF-2 |
| arcA | 717 | 5 | 0.08 | 41 | response regulator in two-component system, anoxic redox control |
| argR | 471 | 4 | 0.05 | 34 | repressor of arginine regulon |
| rplF | 534 | 4 | 0.06 | 33 | 50S ribosomal subunit protein |
| mreC | 1103 | 4 | 0.13 | 28 | longitudinal peptidoglycan synthesis |
Genes are ranked by G scores computed using observed independent nonsynonymous mutations relative to expected number given gene length (bp). The parenthetical gene name is a synonym. Data are from populations with the ancestral point-mutation rate throughout and other populations before they evolved hypermutability.