Table 4.

Secondary structure content in known MoRFs

Protein (residues in peptide)		GRIM (1-15)	TRAP220 (637-654)	BECN1 (105-130)	p53 (367-388)
Type of MoRF		β-MoRF	α-MoRF	α-MoRF	α- & β- MoRF
Average estimated secondary structure content (%)
Helix (%)	No TFE	0 ± 1	7 ± 3	2 ± 1	6 ± 4
	25% TFE	0 ± 4	62 ± 10	48 ± 2	34 ± 10
	40% TFE	7 ± 7	50 ± 3	55 ± 2	31 ± 1
Strand (%)	No TFE	9 ± 8	29 ± 5	28 ± 7	31 ± 2
	25% TFE	19 ± 14	6 ± 3	12 ± 1	12 ± 4
	40% TFE	22 ± 16	7 ± 6	8 ± 1	18 ± 2
Coil (%)	No TFE	89 ± 7	62 ± 6	65 ± 6	63 ± 2
	25% TFE	72 ± 7	32 ± 11	40 ± 2	54 ± 7
	40% TFE	70 ± 20	43 ± 10	36 ± 2	50 ± 4