Table 5.
Secondary structure content in IDRs with Anchor regions with unidentified binding partners
| Protein (residues in peptide) |
ATG3 (129-158) |
ATG9A (810-839) |
BECN1 (76-105) |
AMBRA1 (527-541) |
GOPC (248-277) |
|
|---|---|---|---|---|---|---|
| Average estimated secondary structure content (%) | ||||||
| Helix (%) |
No TFE | 3 ± 5 | 3 ± 2 | 1 ± 1 | 2 ± 1 | 3 ± 1 |
| 25% TFE | 4 ± 1 | 5 ± 4 | 20 ± 3 | 37 ± 1 | 4 ± 1 | |
| 40% TFE | −3 ± 6 | 4 ± 0 | 33 ± 3 | 50 ± 4 | 20 ± 1 | |
| Strand (%) |
No TFE | 27 ± 8 | 20 ± 4 | 4 ± 2 | 4 ± 4 | 19 ± 4 |
| 25% TFE | 26 ± 3 | 28 ± 2 | 8 ± 6 | 10 ± 5 | 17 ± 6 | |
| 40% TFE | 22 ± 9 | 18 ± 5 | 7 ± 4 | 8 ± 5 | 20 ± 4 | |
| Coil (%) |
No TFE | 63 ± 15 | 76 ± 2 | 95 ± 4 | 95 ± 5 | 79 ± 4 |
| 25% TFE | 67 ± 5 | 59 ± 15 | 53 ± 5 | 53 ± 5 | 78 ± 4 | |
| 40% TFE | 76 ± 10 | 78 ± 5 | 43 ± 8 | 43 ± 9 | 60 ± 4 | |