Table 3.
Correlations between individual tumor marker (glucagon and gastrin) and age, sex, PNETs tumor size, tumor number, tumor location, tumor functional status, AJCC stage, lymph node metastases, and lymphovascular invasion.
| Characteristic | Glucagon | P value | Gastrin | P value | |
|---|---|---|---|---|---|
| Age | 0.428* | 0.098 | 0.297* | 0.191 | |
|
| |||||
| Tumor size | 0.503* | 0.067 | 0.027* | 0.906 | |
|
| |||||
| Tumor number | −0.466* | 0.069 | 0.332* | 0.141 | |
|
| |||||
| Sex (Mean) (SD) |
Male | 2657.5 (2868.6) | 0.051 | −20.3 (53.9) | 0.876 |
| Female | −8.1 (46.7) | 251.4 (942.7) | |||
|
| |||||
| Tumor location (Mean) (SD) |
Head/neck | −14.5 (3.5) | 0.751 | −10.0 (NA) | 0.563 |
| Body/tail | 1135.2 (2244.6) | 4.3 (117.6) | |||
|
| |||||
| Tumor functional status (Mean) (SD) |
F | 389.0 (872.0) | 1.000 | 56.3 (124.7) | 0.393 |
| NF | 1265.4 (2492.6) | 193.3 (864.1) | |||
|
| |||||
| AJCC stage (Mean) (SD) |
I | 1234.0 (2381.1) | 0.914 | −13.3 (46.8) | 0.548 |
| II | 1608.0 (3261.4) | 162.0 (220.2) | |||
|
| |||||
| LNM (Mean) (SD) |
Yes | −22.7 (29.4) | 0.629 | 188.0 (NA) | 0.571 |
| No | 2013.0 (3093.7) | 43.5 (166.9) | |||
|
| |||||
| LVI (Mean) (SD) |
Yes | 3255.5 (4588.4) | 0.267 | −70.0 (NA) | 0.222 |
| No | 915.6 (2097.0) | 59.5 (148.5) | |||
PNETs=pancreatic neuroendocrine tumors; AJCC=American Joint Committee on Cancer; F=functioning; NF=non-functioning; LNM=lymph node metastases; LVI=lymphovascular invasion.
*
Spearman correlation