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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Pain. 2016 Sep;157(9):2024–2032. doi: 10.1097/j.pain.0000000000000608

Figure 5.

Figure 5

(A) Representative western blotting images and quantification of GLT-1 and α-tubulin in the right LC from vehicle or valproate treated SNL rats (see Figure 4) with repeated intra-LC injections of the control (8.3 pmol/0.5 μl) or GLT-1 (8.3 pmol/0.5 μl) siRNA for last 5 days. Data (mean + SD) are presented as ratio to α-tubulin. (B) SNL rats treated with valproate and siRNA received intraperitoneal gabapentin (100 mg/kg). Withdrawal thresholds in the right hindpaw were measured prior to (baseline) and one hour after gabapentin administration. Data (mean + SD) are presented as change from baseline.