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. Author manuscript; available in PMC: 2017 Aug 15.
Published in final edited form as: Life Sci. 2016 Feb 17;159:90–96. doi: 10.1016/j.lfs.2016.02.067

Fig. 4. Linagliptin treatment does not ameliorate an increase in middle cerebral artery TLR2 expression.

Fig. 4

TLR2 expression was increased in MCAs from diabetic rats, indicated by the areas of brown staining on immunohistochemical sectioning (40X magnification). This increase was predominately noted in the medial layer of the artery, suggesting that TLR2 is increased in vascular smooth muscle cells in diabetes. Linagliptin treatment had no significant effect on the level of TLR2 expression in diabetic MCAs. Representative images from n=3–4/group shown.