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. Author manuscript; available in PMC: 2017 Aug 15.
Published in final edited form as: Life Sci. 2016 Feb 17;159:90–96. doi: 10.1016/j.lfs.2016.02.067

Fig. 5. Linagliptin treatment reduces TLR2 expression in brain microvascular endothelial cells from diabetic and nondiabetic rats.

Fig. 5

Primary BMVECs from diabetic animals (Diabetic Veh.) exhibited a reduction in TLR2 expression compared to BMVECs from control animals (Nondiabetic Veh.). Treatment with linagliptin 100 nM significantly reduced TLR2 expression in cells from both diabetic and nondiabetic rats. Results are given as mean ± SEM, n=3/group, *=p<0.05 vs. Nondiabetic Veh., #=p<0.05 vs. Diabetic Veh.