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. 2016 Aug 1;233:3371–3381. doi: 10.1007/s00213-016-4379-6

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Visual predictive checks (VPC): 95 % prediction intervals around the 5th, 50th and 95th percentiles are shown for the final model after analysis of group 1 data alone, overlaid to group 1 observed 5th, 50th and 95th percentiles (a), and after analysis of the combined dataset overlaid to group 1 observed 5th, 50th and 95th percentiles (b), and overlaid to group 2 observed 5th, 50th and 95th percentiles (c)