Table 4.
Association of clinical and echocardiographic variables with exercise pulmonary artery systolic pressure.
Univariate | Multivariate model 1 | Multivariate model 2 | ||||
---|---|---|---|---|---|---|
β coefficient (s.e.m.) | P value | β coefficient (s.e.m.) | P value | β coefficient (s.e.m.) | P value | |
Age per 10 year | 1.6 (0.3) | <0.0001 | 1.03 (0.37) | 0.006 | ||
Female sex | −0.51 (0.8) | 0.54 | ||||
Body mass index (kg/m2) | 0.16 (0.09) | 0.08 | 0.23 (0.09) | 0.01 | ||
TR peak velocity at rest (m/s) | 17.4 (1.4) | <0.0001 | 18.1 (1.5) | <0.0001 | ||
Pulse pressure at rest (per 10mmHg) | 1.71 (0.3) | <0.0001 | 0.68 (0.3) | 0.01 | 1.38 (0.3) | <0.0001 |
Systolic BP at rest (per 10mmHg) | 1.15 (0.2) | <0.0001 | ||||
History of hypertension | 3.93 (0.9) | <0.0001 | ||||
Current or prior smoker | 1.13 (0.9) | 0.2 | ||||
Duration of exercise (min) | −0.70 (0.17) | <0.0001 | ||||
Cardiac index with exercise (mL/min/m2) | −0.007 (0.2) | 0.97 | ||||
Systolic BP post exercise (per 10mmHg) | 0.02 (0.008) | 0.04 | 0.4 (0.2) | <0.02 | ||
Pulse pressure post exercise (per 10mmHg) | 0.02 (0.009) | 0.04 | 0.4 (0.2) | 0.05 |
Multivariate analysis with (model 1) and without (model 2) the inclusion of tricuspid regurgitant peak velocity at rest.