Table 2. Reaching glucose thresholds during the 48-hour continues glucose monitoring period stratified by insulin resistance.
| HOMA-IR <2.5 (n = 48) |
HOMA-IR ≥2.5 (n = 63) |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| % children (n) | Median time in minutes per 48 h | % of the timeb | % of the total time (n = 111)c | % children (n) | Median time in minutes per 48 h | % of the timeb | % of the total time (n = 111)c | ||
| Sensor glucose <3.0 | Overall | 17% (8) | 55 (5–395) | 4.6% | 0.8% | 16% (10) | 78 (15–310) | 3.5% | 0.6% |
| mmol/L | Daya | 8% (4) | 28 (5–50) | 1.5% | 0.1% | 6% (4) | 55 (15–100) | 3.1% | 0.2% |
| Nighta | 17% (8) | 55 (45–350) | 11.1% | 1.9% | 14% (9) | 60 (15–210) | 7.9% | 1.1% | |
| Sensor glucose <3.9 | Overall | 73% (35) | 310 (25–1265) | 11.5% | 8.4% | 75% (47) | 170 (15–890) | 9.1% | 6.8% |
| mmol/L | Daya | 58% (28) | 75 (15–295) | 5.6% | 3.3% | 49% (31) | 55 (5–480) | 6.1% | 3.0% |
| Nighta | 71% (34) | 228 (25–970) | 23.8% | 16.9% | 70% (44) | 142 (5–725) | 18.8% | 13.2% | |
| Sensor glucose ≥3.9–<7.8 | Overall | 100% (48) | 2693 (1615–2880) | 91.2% | 91.2% | 100% (63) | 2755 (1990–2880) | 92.1% | 92.1% |
| mmol/L | Daya | 100% (48) | 1752 (1505–1800) | 96.0% | 96.0% | 100% (63) | 1770 (1320–1800) | 95.4% | 95.4% |
| Nighta | 100% (48) | 965 (110–1080) | 83.0% | 83.0% | 100% (63) | 1015 (355–1080) | 86.6% | 86.6% | |
| Sensor glucose ≥6.7 | Overall | 58% (28) | 113 (10–875) | 6.4% | 3.8% | 70% (44) | 148 (5–925) | 8.1% | 5.6% |
| mmol/L | Daya | 58% (28) | 85 (10–595) | 8.3% | 4.9% | 70% (44) | 105 (5–925) | 10.9% | 7.6% |
| Nighta | 19% (9) | 75 (5–280) | 10.2% | 1.9% | 25% (16) | 78 (5–325) | 9.3% | 2.4% | |
| Sensor glucose ≥7.8 | Overall | 27% (13) | 15 (5–185)e | 1.8% | 0.5% | 24% (15) | 105 (15–400)e | 4.5% | 1.1% |
| mmol/L | Daya | 23% (11) | 15 (5–185)d | 3.1% | 0.7% | 22% (14) | 108 (5–390)d | 7.3% | 1.6% |
| Nighta | 4% (2) | 18 (5–30) | 1.6% | <0.1% | 8% (5) | 30 (10–50) | 3.1% | 0.2% | |
| Sensor glucose >9.0 | Overall | 4% (2) | 50 (30–70) | 1.7% | <0.1% | 5% (3) | 45 (30–115) | 2.2% | 0.1% |
| mmol/L | Daya | 4% (2) | 50 (30–70) | 2.8% | 0.1% | 5% (3) | 45 (30–115) | 3.5% | 0.2% |
| Nighta | 0% (0) | 0 | 0% | 0% | 0% (0) | 0 | 0% | 0% | |
| Sensor glucose >10.0 | Overall | 2% (1) | 40 | 1.4% | <0.1% | 3% (2) | 20 (15–25) | 0.7% | <0.1% |
| mmol/L | Daya | 2% (1) | 40 | 2.2% | <0.1% | 3% (2) | 20 (15–25) | 1.1% | <0.1% |
| Nighta | 0% (0) | 0 | 0% | 0% | 0% (0) | 0 | 0% | 0% | |
| Sensor glucose ≥11.1 | Overall | 1% (1) | 15 | 0.5% | <0.1% | 0% (0) | 0 | 0% | 0% |
| mmol/L | Daya | 2% (1) | 15 | 0.8% | <0.1% | 0% (0) | 0 | 0% | 0% |
| Nighta | 0% (0) | 0 | 0% | 0% | 0% (0) | 0 | 0% | 0% | |
Percentage of children reaching certain glucose thresholds at any time during the 48-hour continues glucose monitoring period; Data presented as median (minimum–maximum). HOMA-IR = Homeostatic Model Assessment of Insulin Resistance; Insulin resistance = HOMA-IR ≥2.5.
aDay = 07:00 am–10:00 pm. Night = 10:00 pm–07:00 am.
b% of the time was calculated for the group of children who reached the certain glucose threshold.
c% of the time was calculated for the complete group of children.
dSignificant difference between the median time in minutes between the two HOMA-IR groups at the 0.05 level.
eSignificant difference between the median time in minutes between the two HOMA-IR groups at the 0.01 level.