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. 2016 Aug 18;6:31869. doi: 10.1038/srep31869

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Vesicles were isolated via TEI precipitation from sera of rats recovering from PHx and RNAs were isolated from VEP fractions of sera. qPCR data were median normalized as described in ref. 52. Data are represented as average ± standard deviation. Statistical analysis was performed by One-Way Anova (day 0; n = 3) versus individual groups (day 2, 4 and 6; n = 3 within each group) for each miRNA. *P ≤ 0.05; **P ≤ 0.01.