Figure 1. Domain structure of Sona and generation of sona mutants.

(a) Domain structures of mammalian ADAMTS16, C. elegans MIG-17 and Drosophila Sona. The regions used to generate RNAi lines and those used to generate Sona-Pro antibody and Sona-C antibody were marked with black lines. (b) Three difficiency lines were shown with the genomic map of the region including the sona gene. The dashed lines represent the deleted regions in the difficiencies, and the sona gene is drawn as a pointed blue bar. Red asterisk indicates a mutation site of premature truncation in sona¹³ mutant, which was not produced by P element excision but by spontaneous mutation. The left and right arrows mark the region deleted in sona mutants by P element excision.