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. 2016 Aug 18;6:31971. doi: 10.1038/srep31971

Figure 6. GO-centric evaluation of the impact of taxon constraints on A. thaliana and S. cerevisiae annotation by sequence-based functional transfer.

Figure 6

(a) Non redundant GO terms retrieved by BLAST hits and grouped by the e-value of the alignment. The lower bright portion of columns represents true positives, that are the GO terms associated in GOA to at least one protein belonging to A. thaliana (left) or S. cerevisiae (right); the upper dark fraction represents false positives (GO terms never associated to A. thaliana or S. cerevisiae proteins). “Open” and “closed” world refer to the treatment of GO terms without any explicit constraint: such terms have been either discarded (closed) or retained (open); (b) Word clouds of the most frequent terms contained in GO definitions of false positive annotations (A. thaliana and S. cerevisiae respectively): turquoise and purple words come from GO terms with no defined constraints from GOC and FunTaxIS, respectively. The size of terms is proportional to their frequency (e.g. “muscle” is found in 74 different GO terms).