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. 2016 May 25;24(9):1235–1243. doi: 10.1038/ejhg.2016.35

Figure 3.

Figure 3

MBD5 gene and protein isoforms. (a) Coding exons of human MBD5 (exons 6–15) are shown in red. Translation of these exons yields protein isoform 1. (b) Protein isoform 1 is composed of a conserved MBD, a proline-rich segment (P-rich), a PWWP domain, and putative nuclear localization signals (NLS). (c) Coding exons of MBD5 (6–9) are shown in red. Translation of these exons yields protein isoform 2. (d) Protein isoform 2 is composed of a conserved MBD domain, a proline-rich segment (P-rich), and putative NLS.