Table 2. Other genes associated with 2q23.1 deletion syndrome.

Gene	OMIM	Cytogenetic location	Functiona
ORC4	*603056	2q22.3-q23.1	Initiation of DNA replication in eukaryotic cells; mutations cause the recessive disorder, Meier–Gorlin syndrome, with severe short stature and microcephaly
EPC2	*611000	2q23.1	Component of an essential chromatin regulatory complex; role in transcription and DNA repair; association with Alzheimer disease; critical co-factors in acute myeloid leukemia
KIF5C	*604593	2q23.1	Role in brain functioning, development, survival, and plasticity by regulating the transport of cargo along microtubules within axons, dendrites, and synapses; mutations cause malformations of cortical development and microcephaly

^aFunctions summarized from Gene and Online Mendelian Inheritance in Man (OMIM) from NCBI.