Table 2. The frequency of DGAT1 variants.
| Variant | Prediction | MAF | Prevalence |
|---|---|---|---|
| Missense | Probably deleterious | 0.004262015 | 55 051.61351 |
| Damaging | 0.00178486 | 313 900.2679 | |
| Total | 0.00141469 | 499 663.2779 | |
| Null | Null | 0.000446295 | 5 020 603.88 |
| Missense and null | Probably deleterious | 0.00470831 | 45 109.69607 |
| Damaging | 0.002231155 | 200 881.7651 | |
| Total | 0.001860985 | 288 744.8552 |
Abbreviation: MAF, mean allele frequency.
Probably deleterious alleles were based on Polyphen-2 (http://genetics.bwh.harvard.edu/pph2/) predictions, whereas the ‘damaging' alleles were based on SIFT (http://sift.jcvi.org) predictions.