Table 2. Specific patient and transplant characteristics and outcomes.
| Patient # |
Age (y) at SCT |
Gender | Diagnosis/ Stage |
Extramedullary Disease |
Prior transplant regimens |
Remission duration after initial HSCT (months) |
Time between previous and current HSCT (months) |
Donor match and relation |
Donor relationship to previous donor |
Graft source |
Graft manipulation |
Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 39 | F | ALL, pre-B/ CR3 | none | TBI/Etop Bu/Flu | 36 | 60.2 | 8/10, related | same | PBSC | none | alive |
| 2 | 8 | M | ALL, pre-B/ CR3 | none | TBI/Thio/Cy | 7 | 10.3 | 10/10, related | same | BM | none | deceased-relapse |
| 3 | 23 | M | ALL, pre-B/ CR3 | none | TBI/Thio/Cy | 4 | 8.4 | 10/10, related | same | BM | none | deceased -relapse |
| 4 | 5.4 | F | ALL, pre-B/ CR3 | none | TBI/Thio/Cy | 6 | 11.2 | 8/10, unrelated | same | BM | none | deceased -relapse |
| 5 | 4.5 | M | ALL, pre-B/ CR3 | CNS | TBI/Thio/Cy | 8 | 11.7 | 10/10, related | same | BM | none | alive |
| 6 | 5.2 | M | ALL, pre-B/ CR2 | CNS | TBI/Cy | 24 | 29.2 | 10/10, unrelated | different | BM | none | alive |
| 7 | 8 | M | ALL, pre-B/ CR2 | CNS | TBI/Thio/Cy | 12 | 15.6 | 10/10, related | same | PBSC | none | alive |
| 8 | 28.8 | F | ALL, pre-B/ CR2 | none | TBI/Thio/Flu | 4 | 8.5 | 10/10, related | same | PBSC | none | deceased -relapse |
| 9 | 9 | F | ALL, pre-B/ CR3 | none | TBI/Cy | 11 | 15.9 | 5/6 & 4/6, unrelated | different | cord | none | alive |
| 10 | 25.9 | M | ALL, pre-B/ CR3 | CNS | TBI/Thio/Flu | 31 | 36.6 | 10/10, unrelated | same | PBSC | CD34+ Isolex/E- | alive |
| 11 | 17.6 | M | ALL, pre-B/ CR3 | Testis, nodal, CNS | TBI/Cy | 72 | 73.9 | 10/10, related | same | BM | none | deceased -relapse |
| 12 | 26.7 | M | ALL, T-cell/ CR2 | 1° bone lesion | TBI/Cy | 24 | 31.2 | 10/10, related | same | PBSC | none | alive |
| 13 | 18.5 | M | AML / CR3 | none | Bu/Flu | 3.3 | 13.8 | 9/10, unrelated | different | PBSC | CD34+ CliniMACS | deceased -relapse |
| 14 | 40.8 | F | AML / CR2 | none | TBI/Thio/Cy | 11 | 14.9 | 10/10, unrelated | same | PBSC | none | deceased -relapse |
| 15 | 18.8 | M | AML / CR2 | none | Bu/Mel/Flu | 8 | 13.3 | 9/10, unrelated | different | PBSC | CD34+ CliniMACS | alive |
| 16 | 38.7 | M | AML / CR3 | none | Bu/Mel/Flu | 45.5 | 49.4 | 8/10, unrelated | same | PBSC | CD34+ CliniMACS | alive |
| 17 | 20.2 | F | AML / CR3 | none | Bu/Cy Mel/Flu | 5 | 8.5 | 9/10, unrelated | different | PBSC | CD34+ CliniMACS | deceased -infection |
| 18 | 43.7 | M | AML / CR3 | CNS | TBI/Thio/Cy | 4 | 9 | 10/10, unrelated | same | BM | none | deceased -TRM |