(A) Diagram of genes surrounding human and mouse tetherin.
(B) Organization of TM-CC genes and their protein products for human Tetherin (GenBank: NP_004326.1), mouse TM-CC(aT) (GenBank: XP_003945491.1), and human PV1 (GenBank: NP_112600.1) proteins. Glycosylation and cysteine residues are indicated as brown Y symbols and stars respectively. Numbers indicate amino acid positions. Structural features of TM-CC(aT) and PV1 are based on predictions using TMHMM, COILS, Pred-GPI and GlycoEP.
See also Figure S1.