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. Author manuscript; available in PMC: 2017 Aug 10.
Published in final edited form as: Cell Host Microbe. 2016 Jul 14;20(2):189–201. doi: 10.1016/j.chom.2016.06.007

Figure 2. Antiviral activity of GPI-modified TM-CC(aT) and PV1 proteins.

Figure 2

(A) Infectious virion yield measured using HeLa TZM-bl indicator cells following transfection with a Vpu-deficient HIV-1 proviral plasmid along with increasing amounts of the indicated unmodified (WT) or GPI-modified (+GPI) Tetherin, TM-CC(aT) or PV1 proteins (RLU= relative light units, mean ± SD, n=3).

(B) Western blot analyses (anti-CA) of cell lysates and virions corresponding to (A). Numbers at the bottom represent virion CA protein levels relative to those obtained in the absence of an inhibitor.

See also Figure S2.