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. Author manuscript; available in PMC: 2017 Aug 10.
Published in final edited form as: Cell Host Microbe. 2016 Jul 14;20(2):189–201. doi: 10.1016/j.chom.2016.06.007

Figure 7. Possible evolutionary scenarios for the emergence of tetherin/tm-cc-gpi gene(s) in the pv1–cilp2 locus.

Figure 7

(A) Tetherin/TM-CC-GPI originated once, prior to the division of sharks from other jawed vertebrate lineages via sequential duplications of pv1 and tm-cc(at).

(B) Tetherin/TM-CC-GPI originated independently in multiple vertebrate lineages via duplications of pv1 and tm-cc(at).

See also Figure S7.