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. 2016 Aug 18;354:i4189. doi: 10.1136/bmj.i4189

Table 2.

Changes in market share of marketed drugs and association of regional prescribing with all payments, payments to specialists versus non-specialists, and food and education payments versus speaker and consulting payments

Payments Oral anticoagulants Non-insulin diabetes drugs
Market share change* (95% CI) P value Days filled per payment†(95% CI) Market share change* (95% CI) P value Days filled per payment† (95% CI)
All payments to all physicians 0.32 (0.26 to 0.38) <0.001 94 (76 to 112) 0.12 (0.1 to 0.14) <0.001 107 (89 to 125)
Payment by physician type:
 Non-specialists 0.32 (0.23 to 0.41) <0.001 100 (68 to 123) 0.12 (0.01 to 0.15) <0.001 114 (93 to 144)
 Specialists 0.71 (0.58 to 0.84) <0.001 212 (174 to 250) 0.36 (0.25 to 0.47) <0.001 331 (230 to 442)
 P value for difference between groups <0.001 <0.001
Payment type:
For food and beverage, gifts, or educational materials 0.32 (0.23 to 0.41) <0.001 96 (77 to 114) 0.12 (0.01 to 0.14) <0.001 110 (91 to 128)
For speaker fees, consulting fees, honoraria, travel costs, and non-research grants 1.09 (0.21 to 1.98) 0.02 326 (62 to 590) 0.53 (0.24 to 0.81) <0.001 484 (222 to 745)
P value for difference between groups 0.17 0.01

*Percent change in market share for one additional payment per 1000 person years of Part D coverage in an hospital referral region.

†Number of additional prescription days filled of marketed drug associated with an increase of one payment in a region.