Table 6.

Impact of different hypothetical protocols (D-Study) for QUS measurements recorded in transverse view

QUS measurements in transverse view			E = 1
			V = 1			V = 2
			I = 1	I = 2	I = 3	I = 1	I = 2	I = 3
Geometric
Area (CSA)	SYMPT	Φ	0.96	0.97	0.98	0.98	0.99	0.99
		SEM	0.07	0.05	0.05	0.05	0.04	0.03
		MDC90%NORM	20.91	16.58	14.85	15.18	11.97	10.69
	ASYMPT	Φ	0.91	0.94	0.96	0.94	0.97	0.98
		SEM	0.05	0.03	0.03	0.03	0.03	0.02
		MDC90%NORM	18.96	14.50	12.67	14.38	10.89	9.45
Thickness	SYMPT	Φ	0.96	0.97	0.97	0.98	0.98	0.99
		SEM	0.04	0.04	0.03	0.03	0.03	0.03
		MDC90%NORM	14.79	12.85	12.13	11.02	9.41	8.81
	ASYMPT	Φ	0.83	0.90	0.92	0.89	0.94	0.95
		SEM	0.04	0.03	0.03	0.03	0.02	0.02
		MDC90%NORM	17.46	13.18	11.41	13.72	10.24	8.78
Width	SYMPT	Φ	0.82	0.89	0.92	0.90	0.94	0.96
		SEM	0.09	0.06	0.06	0.06	0.05	0.04
		MDC90%NORM	14.69	10.98	9.42	10.44	7.80	6.69
	ASYMPT	Φ	0.80	0.86	0.88	0.88	0.92	0.93
		SEM	0.06	0.05	0.05	0.05	0.04	0.04
		MDC90%NORM	11.61	9.55	8.75	8.56	6.97	6.35
Grayscale histogram
Echogenicity	SYMPT	Φ	0.85	0.89	0.90	0.91	0.94	0.95
		SEM	6.11	5.16	4.81	4.55	3.79	3.50
		MDC90%NORM	16.47	13.91	12.95	12.25	10.20	9.42
	ASYMPT	Φ	0.81	0.88	0.91	0.90	0.94	0.95
		SEM	5.25	3.94	3.39	3.71	2.79	2.40
		MDC90%NORM	13.23	9.93	8.56	9.35	7.02	6.05
Variance	SYMPT	Φ	0.47	0.53	0.55	0.61	0.68	0.70
		SEM	179.83	159.58	152.23	134.27	116.89	110.49
		MDC90%NORM	53.14	47.16	44.99	39.68	34.54	32.65
	ASYMPT	Φ	0.63	0.71	0.75	0.76	0.82	0.85
		SEM	112.00	92.43	84.91	82.42	67.32	61.47
		MDC90%NORM	34.41	28.40	26.09	25.32	20.68	18.89
Skewness	SYMPT	Φ	0.47	0.60	0.66	0.64	0.75	0.80
		SEM	0.19	0.15	0.13	0.13	0.10	0.09
		MDC90%NORM	69.88	53.98	47.51	49.41	38.17	33.59
	ASYMPT	Φ	0.60	0.70	0.75	0.72	0.81	0.84
		SEM	0.15	0.12	0.11	0.12	0.09	0.08
		MDC90%NORM	69.85	55.19	49.35	53.67	41.75	36.94
Kurtosis	SYMPT	Φ	0.38	0.48	0.52	0.52	0.63	0.67
		SEM	0.83	0.68	0.62	0.62	0.50	0.45
		MDC90%NORM	51.01	41.66	38.04	38.09	30.71	27.81
	ASYMPT	Φ	0.45	0.57	0.63	0.56	0.68	0.74
		SEM	0.58	0.45	0.40	0.47	0.36	0.31
		MDC90%NORM	38.08	29.68	26.29	30.68	23.42	20.44
Entropy	SYMPT	Φ	0.27	0.32	0.34	0.40	0.47	0.50
		SEM	0.15	0.13	0.13	0.11	0.10	0.09
		MDC90%NORM	5.17	4.58	4.37	3.82	3.34	3.16
	ASYMPT	Φ	0.63	0.73	0.77	0.75	0.83	0.86
		SEM	0.09	0.07	0.06	0.07	0.05	0.05
		MDC90%NORM	3.02	2.42	2.18	2.30	1.81	1.62
Co-occurrence matrix
Contrast	SYMPT	Φ	0.81	0.85	0.87	0.88	0.92	0.93
		SEM	0.08	0.07	0.06	0.06	0.05	0.04
		MDC90%NORM	21.25	18.16	17.01	15.64	13.20	12.29
	ASYMPT	Φ	0.65	0.75	0.79	0.77	0.85	0.88
		SEM	0.09	0.07	0.06	0.07	0.05	0.05
		MDC90%NORM	22.63	17.82	15.90	16.89	13.17	11.67
Energy	SYMPT	Φ	0.62	0.67	0.69	0.75	0.79	0.81
		SEM	0.02	0.02	0.02	0.02	0.02	0.02
		MDC90%NORM	39.31	35.16	33.67	28.93	25.50	24.25
	ASYMPT	Φ	0.78	0.85	0.87	0.87	0.91	0.93
		SEM	0.02	0.01	0.01	0.01	0.01	0.01
		MDC90%NORM	27.37	21.80	19.60	19.72	15.65	14.03
Homogeneity	SYMPT	Φ	0.86	0.90	0.92	0.92	0.95	0.96
		SEM	0.01	0.01	0.01	0.01	0.01	0.01
		MDC90%NORM	3.61	2.92	2.65	2.55	2.07	1.87
	ASYMPT	Φ	0.76	0.85	0.89	0.85	0.92	0.94
		SEM	0.01	0.01	0.01	0.01	0.01	0.01
		MDC90%NORM	3.82	2.80	2.36	2.80	2.04	1.72