Table I.
Demographics, fertility characteristics and baseline (stimulation day 1) ultrasound scan (USS) and serum hormone levels per treatment group (intent-to-treat population)
| Previously Published Results |
Corrected Results |
|||
|---|---|---|---|---|
| Corifollitropin alfa (n = 756) | rFSH (n = 750) | Corifollitropin alfa (n = 756) | rFSH (n = 750) | |
| Demographics | ||||
| Age (years) | 31.5 (3.3) | 31.5 (3.2) | 31.5 (3.3) | 31.5 (3.2) |
| Body weight (kg) | 68.8 (7.6) | 68.4 (7.3) | 68.8 (7.6) | 68.4 (7.3) |
| BMI (kg/m2) | 24.8 (2.8) | 24.8 (2.7) | 24.8 (2.8) | 24.8 (2.7) |
| Race, n (%) | ||||
| Asian | 21 (2.8) | 21 (2.8) | 22 (2.9) | 22 (2.9) |
| Black | 33 (4.4) | 28 (3.7) | 33 (4.4) | 28 (3.7) |
| Caucasian | 643 (85.1) | 650 (86.7) | 643 (85.1) | 649 (86.5) |
| Other | 59 (7.8) | 51 (6.8) | 58 (7.7) | 51 (6.8) |
| Fertility characteristics | ||||
| Primary infertility, n(%) | 403 (53.3) | 393 (52.4) | 403 (53.3) | 393 (52.4) |
| Duration of infertility (years) | 3.3 (2.4) | 3.2 (2.2) | 3.3 (2.4) | 3.2 (2.2) |
| Cause of infertilitya), n (%) | ||||
| Male factor | 388 (51.3) | 347 (46.3) | 388 (51.3) | 347 (46.3) |
| Tubal factor | 198 (26.2) | 191 (25.5) | 198 (26.2) | 191 (25.5) |
| Endometriosis | 109 (14.4) | 115 (15.3) | 109 (14.4) | 115 (15.3) |
| Other/unexplained | 246 (32.5) | 262 (34.9) | 246 (32.5) | 262 (34.9) |
| First IVF cycle, n (%) | 569 (75.3) | 552 (73.6) | 569 (75.3) | 552 (73.6) |
| Stimulation day 1 | ||||
| Total ovarian volume(mL)b) | 13.2 (8.1) | 13.2 (7.1) | 13.2 (8.1) | 13.2 (7.1) |
| Basal AFC (<11 mm) | 12.3 (4.6) | 12.4 (4.4) | 12.3 (4.5) | 12.4 (4.4) |
| FSH (IU/L) | 6.7 (2.1) | 6.6 (1.9) | 6.7 (2.1) | 6.6 (1.9) |
| LH (IU/L) | 4.8 (2.0) | 4.7 (1.8) | 4.8 (2.0) | 4.7 (1.8) |
| E2 (pmol/L) | 126.1 (39.3) | 124.8 (37.4) | 126.1 (39.2) | 124.8 (37.1) |
| Progesterone (nmol/L) | 1.8 (1.3) | 1.8 (1.4) | 1.8 (1.3) | 1.8 (1.4) |
AFC: antral follicle count, E2: estradiol, rFSH: recombinant FSH.
Numbers are mean (SD) unless otherwise indicated.
a)A patient can have multiple causes of infertility.
b)According to the formula for a polate ellipsoid: 0.523 x longitudinal x antero-posterior x transverse diameters as measured per transvaginal ultrasound.