Table 1.
Analysis of clinical symptom frequency in different distributions of 3243A>G mutation ratio, n
| Clinical symptom frequencies | Low level of mutation ratio (n = 8) | Middle level of mutation ratio (n = 75) | High level of mutation ratio (n = 17) | χ2 | P |
|---|---|---|---|---|---|
| Decreased vision | 3 | 45 | 4 | 6.423 | 0.040 |
| Hearing loss | 3 | 18 | 0 | 6.239 | 0.044 |
| Encephalopathy | 5 | 63 | 13 | 2.444 | 0.295 |
| Gastrointestinal disturbance | 6 | 56 | 5 | 13.089 | 0.001 |
| Diabetes | 1 | 8 | 1 | 0.413 | 0.813 |
| Growth impairment | 6 | 59 | 12 | 0.530 | 0.767 |
| Myopathy | 4 | 56 | 16 | 6.097 | 0.047 |
| Heart disease | 4 | 26 | 5 | 1.028 | 0.598 |
| MRI/CT changes | 5 | 52 | 11 | 0.257 | 0.879 |
| Elevated lactate | 5 | 55 | 10 | 1.622 | 0.444 |
Low level: A mutation ratio range 0–30%; Middle level: A mutation ratio range 31–60%; High level: A mutation ratio range 61–100%; MRI: Magnetic resonance imaging; CT: Computed tomography.