Table 1.
First author | Number of patients | Gender/age (years) | Published journal year | BMI (kg/m2) | Polysomnography parameters | Therapy | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
AHI (events/h) | Minimal SaO2 | Stage N1 | Stage N2 | Stage N3 | Stage REM | ||||||
Guilleminault | 3 | N/R/N/R | Annu Rev Med 1976;27:465-84 | N/R | N/R | N/R | N/R | ↑ | ↓↓ | Generally normal | N/R |
Guilleminault | 2 | Male/N/R | Arch Intern Med 1977;137:296-300 | N/R | N/R | N/R | N/R | N/R | N/R | N/R | N/R |
Everaert | 1 | Male/35 | J Urol 1995;153:1236 | N/R | 36 | N/R | N/R | N/R | N/R | N/R | CPAP |
Brown | 1 | Male/26 | West J Med 1995;163:478-80 | 37.33 | 48.1 | 46% | N/R | N/R | N/R | N/R | CPAP |
Yokoyama | 1 | Male/53 | Urology 1995; 45:150-4 | 34.63 | N/R | 36% | N/R | ↓↓ | ↓↓ | N/R | Imipramine and acetazolamide |
Ulfberg | 1 | Male/68 | Scand J Urol Nephrol 1996;30:135-7 | N/R | N/R | 30% | N/R | N/R | N/R | N/R | CPAP |
Arai | 1 | Female/53 | Sleep 1997;20:158-9 | 34.63 | 52.6 | 35% | 41.5% | 42% | 2.5% | 14% | Imipramine and dental appliance |
Steers | 1 | Male/60 | Lancet 1997;349:1604 | 36.95 | 47.5 | 87.5% | N/R | N/R | N/R | N/R | CPAP |
Kramer | 5 | Male/37.0 ± 3.1 | Chest 1998;114:634-7 | 38.6 ± 2.1 | 107.4 ± 7.7 | 73.2 ± 2.7 | N/R | N/R | N/R | N/R | CPAP |
Arai | 1 | Female/53 | Psychiatry Clin Neurosci 1999;53:319-20 | 34.63 | 52.6 | 35% | N/R | 42% | 2.5% | 14% | Imipramine and acetazolamide |
Cao | 1 | Female/56 | Chin Med J 2010;123:3328-61 | 29.55 | 70.24 | 68% | N/R | N/R | N/R | N/R | CPAP |
Dushianthan | 1 | Male/41 | Br J Hosp Med (Lond) 2010;71:532-3 | 32 | 80.6 | N/R | N/R | N/R | N/R | N/R | CPAP |
N/R: Not reported; ↑: Elevated; ↓↓: Markedly reduced; REM: Rapid eye movement; BMI: Body mass index; AHI: Apnea-hypopnea index; CPAP: Continuous positive airway pressure.