Table 3.
Age, batch-adjusted Pearson correlations between log-transformed concentrations of uric acid and markers of oxidative stress and inflammation
| Biomarkers | n | r | P |
|---|---|---|---|
| F2-IsoPs (ng/mg) | 657 | −0.18 | <0.0001 |
| F2-IsoP-M (ng/mg) | 630 | 0.01 | 0.75 |
| CRP (mg/L) | 755 | 0.42 | <0.0001 |
| PGE-M (ng/mg) | 394 | 0.12 | 0.02 |
| IL-6 (pg/mL) | 658 | 0.13 | <0.0001 |
| sGP130 (pg/mL) | 618 | 0.04 | 0.38 |
| sIL-6R (pg/mL) | 618 | 0.06 | 0.16 |
| IL-1β (pg/mL) | 658 | −0.002 | 0.96 |
| TNF-α (pg/mL) | 658 | 0.19 | <0.0001 |
| sTNF-R1 (pg/mL) | 618 | 0.06 | 0.17 |
| sTNF-R2 (pg/mL) | 618 | 0.14 | <0.0001 |
Abbreviations: CRP: C-reactive protein; F2-IsoPs: 15-F2t-isoprostanes; F2-IsoP-M: 2,3-dinor-5,6-dihydro-15-F2t-isoprostanes; IL-1β: interleukin 1β; IL-6: interleukin 6; PGE-M: prostaglandin E2 metabolite; sGP130: soluble GP130; sIL-6R: soluble IL-6 receptor; sTNF-R1: soluble tumor necrosis factor receptor 1; sTNF-R2: soluble tumor necrosis factor receptor 2; TNF-α: tumor necrosis factor α.