Table 4. Characteristics of Women Who Did Not Undergo RRSO and Received TVUS for Ovarian Cancer Screening in the Past Yeara.
| No. (%) | ||||
|---|---|---|---|---|
|
|
||||
| Characteristic | No TVUS (n = 596) | TVUS (n = 156) | Adjusted OR (95% CI) | P Value |
| BRCA result | ||||
| Uninformative | 491 (81.7) | 110 (18.3) | 1 [Reference] | |
| Positive | 15 (29.4) | 36 (70.6) | 9.5 (4.3-21.0) | <.001 |
| True-negative | 90 (90.0) | 10 (10.0) | 0.2 (0.1-0.5) | <.001 |
| Age at survey, y | ||||
| <40 | 70 (67.3) | 34 (32.7) | 1 [Reference] | |
| 40-49 | 164 (76.3) | 51 (23.7) | 1.5 (0.7-2.9) | .27 |
| 50-59 | 197 (83.5) | 39 (16.5) | 0.9 (0.4-1.8) | .75 |
| ≥60 | 165 (83.8) | 32 (16.2) | 1.1 (0.5-2.3) | .85 |
| Race | ||||
| Nonwhite | 93 (78.2) | 26 (21.8) | 1 [Reference] | |
| White | 503 (79.5) | 130 (20.5) | 0.9 (0.5-1.6) | .60 |
| Ashkenazi Jewishb | ||||
| No | 333 (80.0) | 83 (20.0) | 1 [Reference] | |
| Yes | 233 (78.2) | 65 (21.8) | 0.9 (0.6-1.5) | .79 |
| Income-producing assets, $ | ||||
| ≤100 000 | 114 (78.1) | 32 (21.9) | 1 [Reference] | |
| 100 001-500 000 | 191 (74.9) | 64 (25.1) | 0.9 (0.5-1.7) | .73 |
| 500 001-1 000 000 | 86 (86.0) | 14 (14.0) | 0.5 (0.2-1.1) | .09 |
| ≥1 000 001 | 205 (82.1) | 46 (18.3) | 1.1 (0.6-1.9) | .85 |
| Testing site | ||||
| SFGH | 48 (87.3) | 7 (12.7) | 1 [Reference] | |
| Diller | 548 (78.6) | 149 (21.4) | 2.3 (0.8-6.6) | .12 |
| BMI, mean (SD) | 24.5 (5.7) | 24.1 (5.1) | 1.0 (0.9-1.0) | .33 |
| No. of live births | ||||
| 0 | 167 (74.6) | 57 (25.4) | 1 [Reference] | |
| 1 | 130 (79.8) | 3 (20.2) | 1.2 (0.7-2.0) | .60 |
| ≥2 | 296 (82.0) | 65 (18.0) | 1.0 (0.6-1.6) | .91 |
| Personal history of breast cancer | 394 (83.5) | 78 (16.5) | 0.5 (0.3-0.9) | .01 |
| First-degree relative with breast cancer | 242 (80.1) | 60 (19.9) | 0.8 (0.5-1.1) | .19 |
| First-degree relative with ovarian cancer | 62 (60.8) | 40 (39.2) | 3.1 (1.8-5.6) | <.001 |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); Diller, Helen Diller Family Comprehensive Cancer Center; OR, odds ratio; RRSO, risk-reducing salpingo-oophorectomy; SFGH, San Francisco General Hospital; TVUS, transvaginal ultrasonography.
a
Five participants did not respond to the survey question about TVUS.
b
Thirty-eight participants responded that they did not know whether they had Ashkenazi Jewish ancestry.