Table 3.
Perinatal outcomes
| Metformin group (n = 324) | Diet group (n = 175) | Significance | |
|---|---|---|---|
| Congenital abnormalities | |||
| Major, n (%) | 1 (0.3) | 1 (0.6) | NS |
| Minor, n (%) | 22 (6.8) | 13 (7.4) | NS |
| Birth weight (BW) (g), mean ± SD | 3387.3 ± 519 | 3429.9 + 535 | NS |
| BW centile, mean ± SD | 49.4 ± 31.1 | 52.1 ± 32.6 | NS |
| BW centile >90, n (%) | 41 (12.7) | 35 (20) | P < 0.01 |
| BW centile < 10, n (%) | 25 (7.7) | 25 (14.3%) | P < 0.01 |
| Preterm < 37 weeks, n (%) | 11 (3.4) | 2 (1.1) | NS |
| Jaundice requiring phototherapy | 23 (7.1) | 2 (1.1) | P < 0.05 |
| Hypoglycaemia | 21 (6.5) | 6 (3.3) | NS |
| Neonatal unit admissions | 33 (10.2) | 12 (6.6) | NS |
| Shoulder dystocia | 3 (0.9) | 2 (1.1) | NS |
NS, non-significant; BW, birth weight