Table 1.
Lipid profile in pregnancy
| Author | Study design | Subjects | Gestational groups | Findings | P values |
|---|---|---|---|---|---|
| Piechota et al. (1992)9 | Cross-sectional analysis | 719 pregnant 65 controls |
172 1st trimester 227 2nd trimester 320 3rd trimester |
Lipids and apolipoproteins elevated in 2nd and 3rd trimester | P < 0.001 (compared with controls) |
| Brizzi et al. (1999)6 | Longitudinal case-control study | 22 pregnant 24 controls |
22 women (samples in 1st, 2nd and 3rd trimester) | Lipids and apolipoproteins elevated in 2nd and 3rd trimester | P < 0.01 (2nd, 3rd versus 1st, 3rd versus 2nd trimester) |
| Lippi et al. (2007)10 | Cross-sectional analysis | 57 pregnant 21 controls |
20 (1st trimester) 20 (2nd trimester) 17 (3rd trimester) |
Lipids and apolipoprotein A elevated in 2nd and 3rd trimester | |
| Husain et al. 11 | Case-control study | 50 pregnant 100 controls |
50 (2nd trimester) | All lipids elevated in pregnancy | P < 0.001 (compared with controls) |
| Bartels et al. (2011) (Unpublished data) | Cross-sectional analysis | 222 pregnant | 48 (11–14 weeks) 50 (19–23 weeks) 32 (27–29 weeks) 45 (35–37 weeks) 47 (postnatal) |
Lipids are progressively elevated throughout pregnancy but start to fall postpartum | P < 0.001 (2nd, 3rd trimester versus 1st trimester, postnatal) |