Table 3.
Preoperative, intraoperative and postoperative factors and early death
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Odds ratio (95% CI) | p value | Odds ratio (95% CI) | p value | |
| Preoperative factors | ||||
| Age ≥85 years | – | – | ||
| Gender (male) | 0.71 (0.11–4.49) | 0.711 | ||
| Pre NYHA IV | 2.44 (0.37–16.0) | 0.338 | ||
| Hypertension | 1.83 (0.19–17.4) | 0.592 | ||
| Diabetes mellitus | 5.50 (0.84–36.0) | 0.075 | ||
| Dyslipidaemia | 0.55 (0.06–5.17) | 0.592 | ||
| Obesity | 1.94 (0.19–19.6) | 0.569 | ||
| Smoking | 1.34 (0.14–13.2) | 0.801 | ||
| COPD | 5.58 (0.47–66.5) | 0.131 | ||
| Re-operation | 8.50 (0.63–114.9) | 0.107 | ||
| Cardiac dysfunction (EF <35%) | 21.5 (2.19–210.6) | 0.009 | 18.6 (0.83–418.7) | 0.658 |
| Severe CKD (eGFR <30 ml/min/1.73m2) | 31.0 (3.07–312.8) | 0.004 | 0.67 (0.004–103.6) | 0.877 |
| Hemodialysis | 24.8 (3.17–193.1) | 0.002 | 19.2 (0.09–4265.1) | 0.284 |
| Cerebrovascular disease | 3.25 (0.30–34.9) | 0.306 | ||
| BNP >1000 pg/ml | 6.00 (0.91–39.4) | 0.062 | ||
| Urgent | 5.58 (0.47–66.5) | 0.174 | ||
| Intraoperative factors | ||||
| ACCT ≥180 min | 6.00 (0.91–39.4) | 0.062 | ||
| Isolated AVR | – | – | ||
| + CABG | 16.0 (1.66–154.6) | 0.002 | 19.2 (0.49–1728.3) | 0.105 |
| Dopamine | 0.97 (0.33–2.99) | 0.268 | ||
| Dobutamine | 0.79 (0.12–5.04) | 0.805 | ||
| Norepinaphrine | 19.5 (2.62–145.1) | 0.004 | 20.3 (0.47–881.9) | 0.118 |
| Carperitide | 0.67 (0.11–4.24) | 0.666 | ||
COPD: chronic obstructive pulmonary disease; EF: ejection fraction; CKD: chronic kidney disease; eGFR: estimated glomerular filtration rate; BNP: brain natriuretic peptide; ACCT: aortic cross clamping time; AVR: aortic valve replacement; CABG: coronary arterial bypass grafting