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. 2014 Feb 28;21(1):18–23. doi: 10.5761/atcs.oa.13-00312

Table 2.

Intraoperative blood loss and survival in 1016 patients who underwent lobectomy for lung cancer

Patient number IBL (mL, mean ± SD) p value 5-year survival (%) p value
IBL          
 ≤318 mL 509 176 ± 81   73.6  
 >318 mL 507 713 ± 504 <0.0001a 45.0 <0.0001b
Gender          
 Male 640 525 ± 510   49.8  
 Female 376 307 ± 269 <0.0001a 73.9 <0.0001b
Age          
 <69 553 431 ± 403   62.9  
 ≥69 463 460 ± 499 0.7622a 53.1 0.0082b
Pathologic stage
 IA 402 330 ± 322   81.7  
 IB 220 415 ± 434   62.6  
 IIA 92 499 ± 403   56.9  
 IIB 71 644 ± 609   24.5  
 IIIA 192 568 ± 517   31.8  
 IIIB 10 722 ± 613   20.0  
 IV 29 674 ± 680 <0.0001c 10.2 <0.0001b
 IA–IIB 785 402 ± 408   67.7  
 IIIA–IV 231 588 ± 543 <0.0001a 28.8 <0.0001b
Histologic type
 Ad 660 373 ± 354   63.6  
 Non-Ad 356 577 ± 564 <0.0001a 48.9 <0.0001b
Year of operation
 1983–2002 555 588 ± 485   47.6  
 2003–2012 461 272 ± 328 <0.0001a 72.4 <0.0001b
Total 1016 445 ± 449   58.3  

a: Mann-Whitney U test, b: Log-rank test, c: Kruskal-Wallis test. Ad: adenocarcinoma; IBL: intraoperative blood loss; Non-Ad: non-adenocarcinoma; SD: standard deviation