Fig. 4.
The sensitivity ratio of each of the 5 outputs considered (value and time of peak worm burden, peak faecal egg count, peak of reduction in feed intake and final bodyweight) in relation to each of the model parameters considered (1–12) when a calf was infected with 3500 L3/d. The parameters were firstly the immune parameters (1–9): the combined effect of establishment and mortality on adult worm burdens (maximum, minimum and rate): EMmax (1), EMmin (2), kEM (3); the effect of mortality of adult worms (maximum, minimum and rate): μmax (4), μmin (5), kμ (6); the fecundity (eggs) of female adult worms (maximum, minimum and rate): Fmax (7), Fmin (8), kF (9). The performance parameters (9–12) considered were; the rate of reduction in feed intake dependent on rate of immune acquisition: C1 (10); the rate of protein loss caused by adult worms rWM (11) and by larvae rLB (12). The sensitivity analysis was conducted by the Latin hypercube sampling technique.