Extended Data Figure 10. mTORC1 inhibition by Torin-1 and rapamycin acutely induced the RACs.

a and b, Immunoblots (a) and quantification (b) of the indicated proteins in lysates of HeLa cells treated with 250 nM Torin-1 or 200 nM rapamycin for the indicated time. Data are means ± SD. n=3 biological replicates. *P≤0.05; **P≤0.01; ***P≤0.001; n.s., not significant (two-way ANOVA). Representative results of at least three independent experiments (biological replicates) are shown.