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. 2016 Jul 22;38(3):776–784. doi: 10.3892/ijmm.2016.2689

Figure 3.

Figure 3

Niclosamide decreases the migration of HCT116, SW620 and LoVo colon cancer cells. (A) Niclosamide reduced cell migration as determined by wound-healing analysis. (B) Statistical results of wound-healing assay. (C) Niclosamide inhibits cell migration, as determined by a Transwell assay and crystal violet staining. HCT116, SW620 and LoVo cells were seeded in a Boyden chamber and treated with niclosamide for 48 h and 20% FBS acted as the chemoattractant for the migrating cancer cells. (D–F) Statistical results of Transwell migration assay for HCT116, SW620 and LoVo cells, respectively. Values are the means ± SE of three determinations (*P<0.05, **P <0.01 and *** P<0.001 vs. DMSO).