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. 2016 Aug 18;11(8):e0158667. doi: 10.1371/journal.pone.0158667

Fig 2. Expression of PLAGL2 in paired PCa with adjacent normal prostate tissues and cell lines revealed by qRT-PCR and western blot.

Fig 2

(A) Levels of PLAGL2 mRNA in 25 PCa tissues were significantly higher than those in adjacent noncancerous tissues measured by qRT-PCR (P<0.0001). (B) The PLAGL2 protein level in PCa tissues was upregulated in comparison with adjacent noncancerous tissues measured by Western blot. (C) Western blot indicated the PLAGL2 protein showed higher expression in PCa tissues than in their adjacent normal counterparts. (D) The expression of PLAGL2 mRNA was higher in PCa cell lines (LNCaP, DU145 and PC3) than in RWPE-1 (P<0.0001). (E) Western blot indicated up-regulation of PLAGL2 protein in PCa cell lines (LNCaP, DU145 and PC3) in comparison with RWPE-1.