Table 3. Odds ratios with 95% confidence intervals for use of fall-risk inducing drugs in persons using APDsa compared to persons not using APDa.
| ATC class | Crude | Model 1b | Model 2c | |
|---|---|---|---|---|
| Use of any fall-risk inducing drug | 1.23 (1.19–1.27) | 1.14 (1.10–1.17) | 1.09 (1.06–1.12) | |
| Use of 5 or more fall-risk inducing drug | 1.74 (1.67–1.81) | 1.64 (1.58–1.71) | 1.49 (1.44–1.55) | |
| Use of specific fall-risk inducing drug | ||||
| Opioids | N02A | 2.26 (2.18–2.34) | 2.19 (2.11–2.27) | 2.01 (1.94–2.09) |
| Antipsychotics | N05Ad | 2.43 (2.30–2.56) | 2.30 (2.18–2.43) | 1.46 (1.38–1.55) |
| Anxiolytics | N05B | 2.06 (1.98–2.13) | 1.99 (1.92–2.07) | 1.71 (1.65–1.78) |
| Hypnotics and sedatives | N05C | 1.85 (1.79–1.90) | 1.78 (1.73–1.84) | 1.68 (1.63–1.73) |
| Antidepressants | N06A | 2.57 (2.49–2.64) | 2.53 (2.45–2.60) | 2.19 (2.13–2.26) |
| Vasodilators used in cardiac diseases | C01D | 1.20 (1.14–1.25) | 1.10 (1.05–1.15) | 1.11 (1.07–1.17) |
| Antihypertensives | C02 | 0.81 (0.68–0.96) | 0.80 (0.67–0.95) | 0.84 (0.70–1.00) |
| Diuretics | C03 | 1.08 (1.05–1.11) | 1.00 (0.97–1.03) | 0.97 (0.95–1.00) |
| Beta blocking agents | C07 | 0.69 (0.67–0.71) | 0.67 (0.65–0.69) | 0.70 (0.68–0.72) |
| Calcium channel blockers | C08 | 0.65 (0.62–0.67) | 0.64 (0.61–0.66) | 0.67 (0.64–0.69) |
| Agents acting on the renin-angiotensin system | C09 | 0.69 (0.67–0.71) | 0.69 (0.67–0.71) | 0.72 (0.70–0.74) |
| Alpha-adrenoreceptor antagonists | G04CA | 1.26 (1.17–1.36) | 1.17 (1.09–1.27) | 1.20 (1.11–1.30) |
| Anticholinergic drugse | see methods | 2.33 (2.24–2.42) | 2.32 (2.22–2.41) | 2.13 (2.04–2.21) |
a APDs = anti-Parkinson drugs
b Adjusted for age (continuous) and sex
c Additional adjustment for type of housing (own home / institution)
d N05AN is excluded from N05A
e N04A is excluded from anticholinergic drugs