Table 5. Diagnostic tests of severe periodontitis as a predictor of cytokine concentrations above the median (95% confidence interval in parentheses).
| Sensitivity | Specificity | Positive predictive value | Negative predictive value | |
|---|---|---|---|---|
| IFN-γ | 84.4 (70.5-93.5) | 31.8 (18.6-47.6) | 55.9 (43.3-67.9) | 66.7 (43.0-85.4) |
| IL-10 | 77.8 (62.9-88.8) | 25.0 (13.2-40.3) | 51.5 (39.0-63.8) | 52.4 (29.8-74.3) |
| IL-1β | 73.5 (58.9-85.1) | 20.0 (9.1-35.6) | 52.9 (40.4-65.2) | 38.1 (18.1-61.6) |
| IL-6 | 77.8 (62.9-88.8) | 25.0 (13.2-40.3) | 51.5 (39.0-63.8) | 52.4 (29.8-74.3) |
| IL-8 | 82.6 (68.6-92.2) | 30.2 (17.2-46.1) | 55.9 (43.3-67.9) | 61.9 (38.4-81.9) |
| TNF-α | 77.8 (62.9-88.8) | 25.0 (13.2-40.3) | 51.5 (39.0-63.8) | 52.4 (29.8-74.3) |