Table 2.

DLS, DLE, and DEE results of DOX-BSA-V-NPs prepared at different BSA/DOX⋅HCl ratios (w/w)

BSA/DOX⋅HCl (w/w)	Particle size (nm)	PDI	DLE (%)	DEE (%)
20:1	100.1±0.7	0.139±0.042	4.28±0.23	89.07±5.07
10:1	100.5±1.3	0.122±0.022	8.29±0.049	85.45±6.38
5:1	134.6±4.2	0.150±0.048	13.98±0.24	77.94±1.58
2:1	189.6±5.7	0.245±0.029	27.77±0.50	73.89±1.86

Note: Mean ± standard deviation, n=3.

Abbreviations: BSA, bovine serum albumin; DEE, drug encapsulation efficiency; DLE, drug loading efficiency; DLS, dynamic light scattering; DOX, doxorubicin; DOX⋅HCl, doxorubicin hydrochloride; NPs, nanoparticles; PDI, polydispersity index; V, vanillin; w, weight.