Table 1.

Parameters for single cell model.

DOI: http://dx.doi.org/10.7554/eLife.16125.011

Parameter related to:	Parameter values:
$I_{NaP}$	$g_{\text{NaP}}=0 - 3\text{nS}$; $v_h =-48 \text{mV}$; $s_h=5 \text{mV}$; ${\displaystyle \overline{{\tau }_h}=10000\text{ms}}$; $V_{\text{NaP}}=50 \text{mV}$;
$I_{Na}$	$g_{\text{Na}}=28 \text{nS}$, ${\displaystyle v_{\text{Na}}=50\text{mV};v_m=-40\text{mV};s_m=-6\text{mV};\overline{{\tau }_n}=10\text{ms}}$
$I_{CAN}$	$g_{\text{can}}=0 to 4.5 \text{nS}$; ${\displaystyle K_{\text{can}}=0.74}$ µM
$I_K$	$g_{\text{K}}=11.2 \text{nS}$; $V_{\text{K}}=-65 \text{mV}$
$I_L$	$g_L=2.7 \text{nS}$; $V_L=-60 \text{mV}$
$I_{Ca}$	$g_{\text{ca}}=0.05 \text{nS}$; $V_{\text{ca}}=150 \text{mV}$; $\alpha =0.055$; $V_{\text{PMCA}}=2; K_{\text{PMCA}}=0.3$
ER Ca	$\lambda =0.03$; $f_i=0.0001;$${\displaystyle \left[{\text{IP}}_3\right]=1}$ µM; ${\displaystyle V_i=4}$ µM3 $A=0.0005$; $V_{\text{serca}}=400 \text{aMol}/\text{s}$; $K_{\text{serca}}=0.2; \sigma =0.185$; $L_{\text{IP}3\text{R}}=0.37\text{pL}/\text{s}$; $P_{\text{IP}3\text{R}}=31000 \text{pL}/\text{s}$; ${\displaystyle K_I=1.0}$ µM; ${\displaystyle K_d=0.4}$ µM; ${\displaystyle K_a=0.4}$ µM
Other	$Cm=21\text{pF}$