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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: J Neurosci Res. 2016 Jun 18;94(10):896–906. doi: 10.1002/jnr.23760

Fig. 7. The NE-dependent optostimulation has no effect on hypoglossal neurons in TH-ChR-Mecp2−/Y mice.

Fig. 7

A. Evoked firing activity of an HN from a TH-ChR-Mecp2−/Y mouse. B. The instantaneous firing rate of the HN. Recording traces in i through iii were obtained from their corresponding sites above with expansion. C. Optical NE-ergic stimulation augmented firing activity of HNs in TH-ChR mice, n=9 cells/2 mice. Data are presented as mean ± SE (**, P<0.01; Student’s t-test). D. The same optical NE-ergic stimulation failed to enhance firing activity in TH-ChR mice when phentolamine (10 μM) was added to the perfusion solution (P>0.05, n=4 cells/1 mouse). E. The NE-dependent optostimulation had no significant effect on firing in TH-ChR-Mecp2−/Y mice (P>0.05, n=6 cells/2 mice).