Table 2.

Regional correlation values between MTR and AHI scores in OSA subjects, corrected for age and gender.

Brain Region	CC	Extent (N)	MNI Coordinates (x, y, z)	P-value
L Caudate	−0.69	369	(−18, 19, −2)	< 0.002
R Caudate	−0.67	537	(9, 16, −3)	< 0.003
L Putamen	−0.71	1138	(−29, 10, −2)	< 0.001
L Anterior insula	−0.75	1603	(−33, 11, 2)	< 0.001
L Posterior insula	−0.69	224	(−39, −5, 0)	< 0.002
L Hippocampus	−0.65	18	(−14, −5, −23)	<0.005
L Amygdala	−0.68	95	(−15, −4, −21)	< 0.001
L Hypothalamus	−0.65	31	(−8, 5, −14)	<0.005
L Basal forebrain	−0.73	146	(−14, 5, −18)	< 0.001
R Basal forebrain	−0.67	66	(9, 5, −17)	< 0.003
L Ventral-medial prefrontal cortex	−0.65	72	(−5, 19, −20)	< 0.005
L Genu of Corpus Callosum	−0.65	136	(−14, 17, −12)	<0.005
R Genu of Corpus Callosum	−0.64	112	(8, 16, −8)	<0.005
L Genu of Cingulate	−0.72	378	(−14, 11, −20)	<0.001
R Genu of Cingulate	−0.68	306	(9, 11, −20)	<0.003
L Frontal white matter	−0.70	3224	(−18, 13, −18)	<0.002
L Globus Pallidus	−0.62	27	(−24, −4, 0)	< 0.008
L Superior temporal cortex	−0.64	54	(−47, 14, −12)	< 0.005

OSA: obstructive sleep apnea, SD: Standard Deviation, CC: Correlation Coefficient, N: number of voxels, L: Left, R: Right.