Fig 5. Neurons with spatially diverse shape selectivity have distinct temporal responses across spatial locations.

(A) For two example neurons (rows), the location-specific shape or set of shapes to which the neuron responded preferentially, at all spatially significant locations. Shapes are superimposed at each grid location. The example neuron in the top row is neuron II in Figs 2,3. (B) Normalized temporal response profiles (red, mean ± s.e.m.) to the composite shapes at the spatial locations marked with asterisks in A. The temporal responses were calculated across all stimuli whose responses were above 70% of local peak response. The black solid line indicates baseline response and the black dotted line indicates 4 standard deviations above baseline. Four purely temporal aspects of the response profiles are indicated: t_sig, the time point at which the temporal kernel first reaches significance; ΔT_sig, the period over which the temporal kernel remains significant; t_peak, the time point at which the response reaches its peak; and ΔT_mid, the duration over which the response remains at a level greater than half-way between the peak and baseline response levels. (C) The average pair-wise temporal kernel distance (see Experimental Procedures; average of all values in right column in Supp Fig 4) is plotted against the average pair-wise pattern correlation (average of all values in middle column of Supp Fig 4) for our entire population of neurons. There is a significant negative correlation (Spearman’s ρ = −0.28, p = 0.01) between the two quantities. The vertical bars mark the ranges for the lower, middle and upper third percentiles of the temporal kernel distances used for the analysis in Fig 6C.