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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Psychopharmacology (Berl). 2016 Jul 29;233(18):3417–3427. doi: 10.1007/s00213-016-4391-x

Fig. 2.

Fig. 2

Menthol dose-response function for enhancement of nicotine self-administration at 0.015 mg/kg/infusion. Five minutes prior to the test sessions, the rats (n = 11) received an intraperitoneal injection of menthol at different doses in a Latin-square design. During the sessions, the rats responded on the active lever for nicotine self-administration at 0.015 mg/kg/infusion on an FR5 schedule of reinforcement. The data are expressed as mean ± SEM. **p < 0.01, significant difference from vehicle treatment.