Table 5.

Relationship between risk factors at the individual-, household-, partner-, and school-level and prevalent HIV and HSV-2 infection, among young women enrolled in HPTN 068 at baseline in Agincourt, South Africa March 2011–December 2012

	HIV				HSV-2
	OR (95 % CI)	p	aOR (95 % CI)a	p	OR (95 % CI)	p	aOR (95 % CI)a	p
Individual risk factorsb
Yes	2.87 (1.83–1.49)	<0.0001	2.30 (1.40–3.77)	0.001	5.46 (3.66–8.15)	<0.0001	3.12 (2.03–4.78)	<0.0001*
No	1		1		1		1
Household risk factorsc
Yes	2.30 (1.37–3.84)	0.002	2.21 (1.32–3.71)	0.003	1.99 (1.30–3.04)	0.002	1.92 (1.24–2.97)	0.003
No	1		1		1		1
Partner risk factorsd
Yes	3.76 (2.39–5.91)	<0.0001	3.05 (1.84–5.06)	<0.0001*	6.84 (4.62–10.13)	<0.0001	3.84 (2.52–5.85)	<0.0001*
No	1		1		1		1
School risk factorse
Yes	2.86 (1.81–1.53)	<0.0001*	2.28 (1.32–3.95)	0.003	3.38 (2.26–5.04)	<0.0001*	1.35 (0.85–2.15)	0.2
No	1		1		1		1

^*An asterisk (*) following a p-value indicates that this result would be significant at the 0.05 level after Bonferroni adjustment for multiple comparisons (adjusted models only—100 comparisons are reported in Tables 3 and 5)

^aAge-adjusted ORs, coding age categorically with a dummy variable for every year

^bReports at least one of the following risk factors: 1. No condom use at last sex with at least one of last three partners, 2. Multiple lifetime sex partners, 3. Any alcohol consumption, 4. Ever sex while drunk, 5. Ever sex while on drugs

^cReports at least one of the following risk factors: 1. Single or double orphanhood, 2. Primary caregiver is non-parent, 3. Lowest asset quartile

^dReports at least one of the following risk factors: 1. Older partner (by 5 or more years), 2. Transactional sex with at least one of last three partners, 3. Partner has other partners

^eReports at least one of the following risk factors: 1. Repeated grade, 2. Miss >20 % school days in typical school week