Table 1.

National Prevalence Estimates of Psychotropic Medication^a Use in Patients with Dementia from the Aging, Demographics, and Memory Study (n=414)

	None	Antipsychotic	Sedative-Hypnotic	Antidepressant	Mood Stabilizer
Participants, n	234	56	70	103	13
Overall weighted percent (95% CI)	58.6 (52.4–64.6)	10.9 (7.6–15.3)	19.5 (14.2–26.2)	23.5 (18.8–29.0)	1.5 (0.9–2.7)
Population estimate, millions (95% CIb)	3.9 (3.0–4.8)	0.7 (0.5–1.0)	1.3 (0.8–1.9)	1.6 (1.1–2.0)	0.1 (0.05–0.2)
	n (column weighted percent [95% CI])
Reside in nursing home	33 (6.3 [4.2–9.4])	32 (65.3 [49.1–78.6)]	33 (53.1 [31.3–73.7])	44 (52.7 [34.6–70.1])	6 (39.7 [18.3–65.9])
Dementia stagec
Mild	170 (84.7 [75.8–90.8])	11 (23.6 [7.9–52.6])	29 (59.0 [40.8–74.9])	52 (49.0 [34.8–63.4])	3 (32.6 [12.3–62.5])
Moderate	24 (6.5 [3.2–12.8)]	19 (36.4 [16.8–61.9])	23 (27.6 [14.4–46.3])	26 (24.1 [12.8–40.6])	4 (34.5 [13.5–63.9])
Severe	39 (8.8 [4.8–15.4)]	26 (40.0 [24.8–57.3])	18 (13.5 [6.0–27.4])	25 (26.9 [14.2–45.0])	6 (33.0 [12.0–63.9])
Cholinesterase Inhibitor or memantine	29 (14.1 [7.2–26.9])	18 (38.4 [18.3–63.3])	12 (17.8 [7.8–35.7])	23 (34.4 [19.0–54.0])	4 (30.3 [9.6–64.0])
Other Psychotropic Medication
Antipsychotic	n/ad	n/a	16 (20.0 [9.1–38.5])	20 (20.5 [10.1–37.0])	7 (37.0 [17.0–62.7])
Sedative-hypnotic	n/a	16 (35.8 [16.1–62.0])	n/a	20 (26.1 [14.4–42.6])	6 (43.1 [12.8–79.6])
Antidepressant	n/a	20 (44.2 [22.0–69.0])	20 (31.4 [17.0–50.6])	n/a	8 (47.8 [24.9–71.7])
Mood Stabilizer	n/a	7 (5.2 [2.1–12.5])	6 (3.4 [1.0–10.4])	8 (3.1 [1.3–7.4])	n/a
Any	n/a	32 (65.1 [42.9–82.3])	37 (44.3 [28.1–61.9])	43 (44.7 [29.3–61.3])	12 (82.4 [28.3–98.2])

^aMedication groups are not mutually exclusive

^bCI: confidence interval

^cAs classified by Clinical Dementia Rating Scale (CDR) Score: Mild (CDR 0.5–1.0); Moderate (CDR 2.0); Severe (CDR 3.0–5.0)

^dn/a: not applicable