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The minimum inhibitory concentrations (MICs) of different antibiotics for AB1845 and AB2092.
| Antibiotics | MIC (mg/L) | |
|---|---|---|
| AB1845 | AB2092 | |
| Cefoperazone/sulbactam | 16/8∗ | 128/64 |
| Cefoperazone | >128 | >128 |
| Sulbactam | 32 | 128 |
| Meropenem | 16 | 64 |
| Imipenem | 16 | 64 |
| Doripenem | 32 | 128 |
| Colistin | 2 | 2 |
| Polymyxin B | 1 | 1 |
∗FICI = 0.375; FICI = MIC(A)/MIC(A in combination) + MIC(B)/MIC(B in combination). The bold values showed the increasing MIC of AB1845 compared with AB2092.
