Fig. 3.

PRX3 may be a direct target of DACH1 in vitro. a The luciferase activity was significantly lower when transfected with DACH1 but not empty vectors in both LTEP-α-2 and A549 cells. b Transfection with DACH1 can remarkably downregulate cellular PRX3 expression in both LTEP-α-2 and A549 cells by real-time PCR analysis. c Western blotting analysis for DACH1 and PRX3 expression in wild-type and DACH1 transfected lung cancer cells (LTEP-α-2 and A549). Data are shown as mean ± SEM (n = 3), **p < 0.01