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. 2016 Jan 14;37(7):9077–9088. doi: 10.1007/s13277-015-4555-z

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 4 — Effect of enforced/repressed CDH12 on tumorigenicity in nude mice. a Low expression of CDH12 in SW620 cells induces small nodules in nude mice. b Column graph indicates that the weight (left panel) and size (right panel) of tumor nodules in SW620/shCDH12 group are lower than control groups (*P < 0.05, **P < 0.01). c High expression of CDH12 promotes formation of tumor nodules in nude mice. d Column graph indicates that the weight of tumor nodules in HCT116/CDH12 group is heavier than control groups (left panel). The size of tumor nodules in HCT116/CDH12 group is larger than control group (right panel) (*P < 0.05, **P < 0.01)