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Altered levels of Th2 cytokines in OT-II mice. (A, B) Levels of peripheral Th2 cytokines released by naïve ovalbumin-specific T cells were significantly higher in OT-II mice than for control mice. (C) OT-II mice expressed significantly higher level of IL-4 in the brain than control mice. Values are expressed as the mean ± SEM *p < 0.05, **p < 0.01, and ***p < 0.001 as compared to the control mice.
